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VOL. 11, ISSUE 2 (2026)
Maintenance of Zebrafish in aquaculture facilities and CRISPR - Cas9 -based mutant generation
Authors
Korhale G A
Abstract
Zebrafish (Danio rerio) has emerged as a prominent model
organism in aquaculture and biomedical research due to its rapid development,
genetic similarity to higher vertebrates, and ease of maintenance under
laboratory conditions. Proper maintenance of zebrafish in aquaculture
facilities involves controlled water quality parameters, optimal feeding
regimes, and appropriate stocking densities to ensure healthy growth and
reproduction. Recent advancements in genome editing technologies, particularly
CRISPR–Cas9, have revolutionized functional genomics by enabling precise and
efficient gene modification. CRISPR–Cas9-based mutant generation in zebrafish
allows targeted gene disruption, facilitating the study of gene function,
developmental biology, and disease mechanisms. The integration of optimized
aquaculture practices with advanced molecular tools enhances the reliability
and reproducibility of experimental outcomes. This approach not only
contributes to basic biological research but also holds significant potential
for improving aquaculture species through genetic interventions.
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Pages:43-48
How to cite this article:
Korhale G A "Maintenance of Zebrafish in aquaculture facilities and CRISPR - Cas9 -based mutant generation". International Journal of Advanced Scientific Research, Vol 11, Issue 2, 2026, Pages 43-48
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