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VOL. 10, ISSUE 3 (2025)
Synthesis of zinc oxide nanoparticles using fruit peels of Muskmelon and their biological potential
Authors
Bhupendra Tanwar, Pawan Kumar Kansotiya, Anupama Goyal
Abstract
The growing concern of antibiotic resistance and the need for
sustainable medicines have fuelled interest in plant-based nanotechnology. In
this research, green synthesis of zinc oxide nanoparticles (ZnONPs) from
kitchen waste in the form of bitter gourd (Momordica charantia) fruit
peels was investigated as a sustainable, eco-friendly, and cost-effective
approach compared to traditional processes. The ZnONPs synthesized were tested
for antioxidant, antidiabetic, anti-inflammatory, and antimicrobial properties
and compared with crude plant extracts. The ZnONPs exhibited much improved
bioactivity, with more powerful free radical scavenging (IC₅₀ = 384.10 µg/ml),
α-amylase inhibitory (IC₅₀ = 1114.77 µg/ml), and anti-inflammatory activities
(IC₅₀ = 10395.18 µg/ml) than crude extracts. The enhanced bioefficacy is due to
the surface area and reactivity of nanoparticles and synergistic effects of
bioactive compounds in bitter gourd peels. This research is revealing a double
advantage: the valorization of kitchen waste and the promotion of sustainable
nanotherapeutics. The discovery proposes ZnONPs prepared from fruit peels as potential
agents for fighting oxidative stress, diabetes, and microbial infections and
promoting green nanomedicine development.
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Pages:36-38
How to cite this article:
Bhupendra Tanwar, Pawan Kumar Kansotiya, Anupama Goyal "Synthesis of zinc oxide nanoparticles using fruit peels of Muskmelon and their biological potential". International Journal of Advanced Scientific Research, Vol 10, Issue 3, 2025, Pages 36-38
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