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VOL. 8, ISSUE 2 (2023)
Phytochemical screening and antimicrobial activity of the leaf extract of Vernonia amygdalina (Bitter leaf)
Authors
Okeke Chioma Udoka, Malgwi Adamu Harami, Danladi Kyenpia Habila
Abstract
This study was conducted to determine phytochemicals and antimicrobial
activities of Vernonia amygdalina using standard methods. Results showed that
V. amygdalina contains alkaloids, tannins, saponins, triterpenoids, steroids
and cardiac glycosides that are responsible for its antibacterial activities.
The minimum inhibitory concentration (MIC )results indicates that the aqueous
and methanolic extracts of the plant leaves investigated exhibited
antibacterial activity against Staphylococcus aureus, Streptococcus pneumonia,
Escherichia coli, Pseudomonas aeruginosa and fungi candida albican, while the
minimum bactericidal concentration (MBC) range between 100 – 400 mg/ml. Vernonia
amygdalina leave extracts could therefore be a promising natural antibiotics
with potential than conventionally antibiotics in controlling bacteria and
fungi that can cause diseases.
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Pages:52-56
How to cite this article:
Okeke Chioma Udoka, Malgwi Adamu Harami, Danladi Kyenpia Habila "Phytochemical screening and antimicrobial activity of the leaf extract of <i>Vernonia amygdalina</i> (Bitter leaf)". International Journal of Advanced Scientific Research, Vol 8, Issue 2, 2023, Pages 52-56
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