Dengue fever is a mosquito borne viral disease and rapidly occurring in many parts of world affecting in all age groups [1]. Data was collected from National Vector Borne Disease Control Program, Kamrup Metropolitan District and analyzed statistically. The outcome of this study shows impending epidemics by timely analyzing various data to reduce disease burden. It has been observed that dengue infection is associated with time, place and person. The major preventive measure is mass awareness, disease surveillance, source reductions activities. Prevalence of these diseases is found prominently in the urban areas.