The curative role of vitamin c on alteration in behavioral and morphological characteristics of cyprinus carpio fish after exposed to Malathion
Mohammed Obaid Enad Al-Mansoori, Dr. Moayed Jassim Yass Al-Amari
This study aims to determine of malathion effects in behavior, Feeding and morphological deformation of Cyprinus carpio and protective activity of vitamin C in reduction toxicity. Common carp C. carpio (total n= 75) were exposed to different concentrations (0, 1, 3, 6 and 10 mg/L) of malathion (EC 57) for 28 days. The median lethal concentration (LC50) for 96 hours was computed by the probit method, and was found to be 2.04 mg/L. The fish were exposed to 0.5 mg/L (approximately 1/4 of the 96-h LC50) malathion. A total number of 108 were allocated into six treatment groups (with three replicates): group 1 as control; group2 malathion (0.5 mg/L), group3 malathion (0.5 mg/L) plus vitamin C (300 mg/kg in diet), group4 malathion (0.5 mg/L) plus vitamin C (1000 mg/kg in diet), group5 vitamin C (300 mg/kg in diet) and group6 vitamin C (1000 mg/kg in diet). The experiment was carried on for 28 days. The behavioral changes and morphological deformation were recorded. Fish in malathion groups showed irregular swimming, loss of equilibrium. The main morphological changes were caudal bending. However, this toxic effect was neutralized by the administration of ascorbic acid. Thus, the present results suggest that simultaneous treatment with ascorbic acid may alleviate malathion-induced oxidative stress.