The significance of testa in the lipid profile of wistar rats fed oil extracts of Irvingia gabonensis and Irvingia wombolu
Omale JA, Arogba SS, Omale A
Lipid profiles of experimental wistar rats fed with oil extracts from kernels of Irvingia gabonensis, (Ig) and Irvingia wombolu (Iw) were studied using standard methods. In addition, effect of testa was also investigated on the profiles of the rats. On day zero, before administration of oil extract, rats were sacrificed and this served as the control group. After 7days of oil administration to the rats, the diet containing these oil showed nutritional improvement compared with control. The observation was more significant (p<0.05) after 14 days when increase in HDL cholesterol and reduction in TG and LDL cholesterol levels were pronounced in animals fed with Iw, especially. The Irvingia wombolu (Iw) extracts irrespective of treatment, had stable LDL, increase in TC by 24.6%, a remarkable rise in HDL by 115.8% and a decrease in TG by 6.4%. When effect of testa was examined between the periods of administration, Iwt gave increased values of 178.2% TC, 354.5% HDL and 743% decrease in LDL representing ratio 1:2:5 respectively. The study, therefore, revealed that oil extract of Irvingia kernels contain high levels of phenolic substances capable of inhibiting lipid autoxidation.
Omale JA, Arogba SS, Omale A. The significance of testa in the lipid profile of wistar rats fed oil extracts of Irvingia gabonensis and Irvingia wombolu. International Journal of Advanced Scientific Research, Volume 4, Issue 5, 2019, Pages 09-12