Background: Kids are an exemplification of our fantasy. They are the most powerless gathering in the general public. So youngsters need exceptional consideration to get by with great well-being. Kids are most helpless to illness for various reasons. Scientists have made extraordinary investigations in controlling numerous tyke hood ailment. Antibody, specifically have spared a large number of youthful lives and with appropriate use. Points and Objective-To assess the parent’s knowledge in regards to Rota infection antibody, To find out the association between knowledge scores with selected socio-demographic variables. Material and Methods-The information were gathered from 100 parents of under five kids by purposive inspecting strategies with the utilization organized poll and enlightening plan was utilized. Result-parents of under-five youngsters' having sufficient information 12%, moderate 57%, and deficient 31% in regards to Rota infection antibody for anticipation of looseness of the bowels. Conclusion-The significant end drawn from this examination was that most of the parents of under five children were having sufficient knowledge and very few were having adequate knowledge, the elevated rate 57% parents of under five kids had satisfactory knowledge with respect to rotavirus immunization for counteractive action of the runs.