Background & Objective: MRSA is major nosocomial pathogen that causes severe morbidity and mortality worldwide, they cause variety of infections like bacteremia, endocarditis, UTI, SSI. Objective of the study is to estimate the prevalence of MRSA in clinical specimens and to detect sensitivity pattern of these strains against various antibiotics.

Material & Method: Samples received to the Microbiology department for culture and sensitivity were inoculated on culture media like blood agar, MacConkey agar, nutrient agar. S. aureus was diagnosed on the basis of their growth characteristics on the respective media’s and standard biochemical test. The antibiotic susceptibility testing was done by Kirby Bauer disk diffusion method and zone of inhibition was interpreted as per CLSI guidelines9.

Results: Among 3452 samples received for a period of 6 months from May to October 2018, growth was seen in 2198 (63.67%) samples, Out of these 350 (15.92%) samples were of Staphylococcus aureus, from which 190 (54.28%) samples were MRSA. Majority of MRSA were isolated from pus sample 92 (48.42%) followed by blood 40 (21.05%), urine 34 (17.89%). MRSA were isolated more commonly in males 117 (61.57%) than in females 73 (38.42%). MRSA was most commonly reported in the age group of 10-30 years 89 (46.84%) followed by age group of 30 to 50 years 58 (30.52%), Least number of MRSA was reported in age group less than 10 years 06 (3.1%). Antibiotic susceptibility testing for MRSA showed maximum sensitivity to Vancomycin 100% followed by Gentamicin 86%, Clindamycin 49%, Ciprofloxacin 47%, Erythromycin 29%, Cotrimoxazole 38%.