People abuse drugs for various reasons. It starts with curiosity, then availability and previous drug use and also due to emotional and social pressures. The use of Narcotic analgesia is normally controlled by various regulations and procedures to prevent misuse and to comply with International conventions termed as Narcotic policy. Previous studies have shown that Nurses are having inadequate knowledge regarding Narcotic drug policy. The purpose of this study was to assess the knowledge level of ICU Nurses regarding Narcotic drugs. 10 ICU Nurses were selected through the purposive sampling technique and their knowledge level was assessed by Structured knowledge questionnaire. Mean and standard deviation of knowledge score was calculated in which, the mean value was 8.3 and the standard deviation was 1.89. Thus, the study revealed that there is no association of knowledge scores with selected socio demographic variables regarding Narcotic drugs.