In present survey an attempt has been made to evaluate the bio-control activity of plant extract against certain fungi causing infection on tomato plant during pre-harvesting and post-harvesting condition. The major infection causing fungi are Fusarium oxysporum, Alternaria solani, Pythium ultimum, Phytophthora nicotianae, Aspergillus niger. The plant extract (bulb) of Garlic (Allium sativum L.) proves effective to control the infection caused by above fungi.