The traditional system of medicine plays a significant role in our health care system for the treatment of mankind. Thuja occidentalis is commonly used herb in Ayurvedic medicine. Thuja occidentalis (Northern white cedar) belongs to the family Cupressacae. The plant is highly used by rural people in curing various disorders. Thuja occidentalis has an effective natural origin that has a tremendous future for research as the novelty and applicability of Thuja occidentalis are still hidden. Such things can be overcome through modern scientific research. The present article describes various traditional and medicinal utility of the chemical composition and pharmacological activity of the plant and its constituents.