Family planning is defined by WHO as, a way of thinking & living that is adopted voluntarily, upon the basis of knowledge, attitudes & responsible decisions by individuals & couples, in order to promote the health & welfare of family groups thus contribute effectively to the social development of the country. Descriptive survey approach and descriptive survey design are used in the study to assess the knowledge and practice of family planning methods among the eligible couples at selected areas, Tirupati. 60 Eligible couples are selected by using non probability convenient sampling technique. Data was collected using questionnaire method. The study findings revealed that the knowledge level of eligible couples was determined with mean of 18.55 standard deviation of 3.50. The mean percentage score of practice was computed and it was observed as 6.75 with standard deviation 0.67. The results showed that, eligible couples have moderate knowledge and practice regarding family planning methods.