Outbreaks of Coronavirus 2019 (COVID-19), caused by acute acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), have so far killed more than 3,000 people and infected more than 80,000 in China and beyond places in the world, which leads to disaster for people. Like its virus, SARS-CoV, which created SARS in thousands of people in 2003, SARS-CoV-2 can also be transmitted to bats and cause similar symptoms in the same way. However, COVID-19 has a lower risk and mortality rate than SARS but is more contagious and affects older people than adolescents and more men than women. In response to the rapidly growing number of literature on this emerging disease, this article seeks to provide a timely and complete review of the rapidly evolving research topic. We will look at the basics about epidemiology, etiology, virology, diagnosis, treatment, prognosis, and prevention of this disease. Although many questions still need answers, we hope that this review will help to understand and eliminate the threatening disease.