International Journal of Advanced Scientific Research

International Journal of Advanced Scientific Research


International Journal of Advanced Scientific Research
Vol. 1, Issue 4 (2016)

Solvent evaporation technique: An innovative approach to increase gastric retention


Neeta, Meenu Mehta, Saurabh Satija, Parijat Pandey, Mandeep Dahiya

Floating dosage forms are emerging as a promising novel dosage forms, these can be retained in the stomach for a prolonged period of time and release the active ingredient in a predetermined manner. In exploration of this avenue, different novel strategies have been undertaken for the designing of floating systems including floating microspheres. Polymeric floating microspheres are ideal vehicles for many controlled delivery applications due to their ability to encapsulate a variety of drugs, biocompatibility, high bioavailability and prolonged drug release characteristics. To achieve these goals various techniques have been developed for preparation of floating microsphere, among them solvent evaporation is an effective approach. Present review addresses the general description of the floating system, floating microspheres, solvent evaporation process, various research findings based on solvent evaporation technique.

Pages : 60-67